Vagus nerve stimulation
نویسندگان
چکیده
Vagal nerve stimulation (VNS) was first delivered to patients over 25 years ago with the first patient being implanted in 1988. European Community approval was granted in 1994 and USA (FDA) commercial approval in 19971. VNS currently has a licence in Europe and the UK for the adjunctive treatment of epilepsy refractory to antiepileptic medication. The UK NICE Guidelines for Epilepsy (2012) suggest VNS is indicated ‘for use as an adjunctive therapy in reducing the frequency of seizures in adults (and children) who are refractory to antiepileptic medication but who are not suitable for resective surgery’. NICE specifies that VNS is indicated for patients in whom focal or generalised seizures predominate. The US licence is for refractory focal epilepsy in patients over the age of 12.
منابع مشابه
Protective effects of an interaction between vagus nerve and melatonin on gastric ischemia/reperfusion: the role of oxidative stress
Objectives:Vagal pathways in gastrointestinal tract are the most important pathways that regulate ischemia/reperfusion (I/R). Gastrointestinal tract is one of the important sources of melatonin production. The aim of this study was to investigate probable protective effect of the interaction between vagus nerve and melatonin after I/R. Materials and methods:This study was performed in male rat...
متن کاملVagus nerve stimulation in the treatment of nervous system disease: a review article
The vagus nerve (VN), the longest cranial nerve and an essential part of the parasympathetic system, connects the central nervous system to respiratory, cardiovascular, immune, gastrointestinal, and endocrine systems and is involved in the maintenance of homeostasis by controlling these systems. Vagus nerve stimulation (VNS) is related to any method that would stimulate the vagal nerve via elec...
متن کامل7.01.20 Vagus Nerve Stimulation
Policy [TOP] Vagus nerve stimulation may be considered medically necessary as a treatment of medically refractory seizures. Vagus nerve stimulation is considered investigational as a treatment of other conditions, including but not limited Non-implantable vagus nerve stimulation devices are considered investigational for all indications.
متن کاملThe effect of thyroid hoemones on basal and vagally stimulated gastric acid and pepsin secretion in rat
thyroid hoemones effect gastric acid and pepsin secretion.however exact machanism(s) are not clear.this study was performed to compare the effect of vagal stimulation on acid an pepsin secretion in hypothyroid,hyperthyroid and control rars.each group consisted of 8 male and female rats(N-mari) weighing 246+_9 gr.hypo and hyperthyroid states were induced by administretion of methimazol (50mg/l i...
متن کاملThe Inhibitory Effect of Ziziphora clinopodioides Lam. on Gastric Acid Output at Basal, Vagotomized and Vagal Stimulated Conditions in Rat
Objective(s) Ziziphora clinopodioides Lam. is a plant widely used in Iranian traditional medicine for gastrointestinal disorders. Several reports have demonstrated antibacterial (Helicobacteria pylori), antioxidant and antiinflammatory properties of Z. clinopodioides. The aim of this study was to investigate the effects of aqueous- ethanol extract of Z. clinopodioides on rat’s gastric acid ou...
متن کاملTranscutaneous Auricular Vagus Nerve Stimulation on Neurological and Mental Disorders: From Germination to Future
Auricular therapies have been applied to diseases since ancient times. Inspired by auricular acupuncture of TCM, and to overcome the disadvantages classic vagus nerve stimulation (VNS), we developed transcutaneous auricular vagus nerve stimulation (taVNS). It was applied to neurological and mental disorders, and also shows a bright prospect to these diseases.
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